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Such methodology produces, at best, solely conclusions, based on available evidence and the assumptions used to evaluate the data.
There is the inherent possibility that an unknown factor will alter the conclusion, similarly as was the unexpected discovery of black swans in Australia, when the whole world “knew” all swans were white.
Such calculations rely upon many assumptions about mutation rate, recombination rate, and other factors, that are known to vary widely.
All of this entails retrospective calculations about events in the far distant past, for which we have no directly verifiable data.
They think that the latest findings in paleoanthropology and genetics render a literal pair of first true human parents to be “scientifically impossible.” The prevailing assumption underlying media reports about human origins is that humanity evolved very gradually over vast periods of time as a population (a collection of interbreeding organisms), which itself originally evolved from a (human/chimpanzee) common ancestor millions of years ago.
Therefore, we are not seen as descendants of the biblical Adam and Eve.
Yet, contrary to current skepticism, a real Adam and Eve remain credible—both in terms of Catholic doctrine and sound natural science.
Fourth, specific scientific arguments against Adam and Eve have proven not as forceful as many presently believe (Gauger 2012).
For example, some have claimed that effective population size estimates for the last several million years would not permit just two true humans to have lived during that time.
Irrational animals, including subhuman primates, are capable of complex sentient behaviors often approaching or imitating the rational activities of true man.
But an animal either possesses a spiritual, intellectual soul or not.
Still, the technical concept of average effective population size estimates should not be confused with an actual “bottleneck” (a temporarily reduced population) which may be much smaller.